Kratimenos Lab

About the Lab

The Kratimenos Lab studies how premature birth disrupts brain development — especially the cerebellum — and drives lifelong neurodevelopmental problems. We take a translational approach, pairing human neonatal data with mouse models to map the cellular and molecular damage caused by prematurity and to test therapies like physiotherapy and enrichment. Our work also reaches into NEC and SIDS, two of prematurity's most serious complications.

Lab Focus Areas
Neonatal brain injury

Cerebellar neural circuits and behavior

Development neurobiology
Contact
Panagiotis Kratimenos, MD, PhD Principal Investigator panagiotis.kratimenos @childrensnational.org

Featured Publications

Prematurity reprograms cerebellar development and long-term behavior
Georgios Sanidas, Gabriele Simonti, Javid Ghaemmaghami, Kyla Woyshner, Nora Wolff, Chad Byrd, Maria Triantafyllou, Courtney Lowe, Henry Salisbury, Evan Goldstein, Aaron Sathyanesan, Robinson Vidva, Ioannis Koutroulis, Genevieve Stein-O'Brien, Dimitrios N Sidiropoulos, Vittorio Gallo, Panagiotis Kratimenos PMID: 40777437 bioRxiv [Preprint] 2025.07.22.664624. Jul 24, 2025
Intrinsic gestational timing governs human cerebellar development after preterm birth
Georgios Sanidas, Gabriele Simonti, Javid Ghaemmaghami, Kyla Woyshner, Robinson Vidva, Nora Wolff, Maria Triantafyllou, Courtney Lowe, Abhya Vij, Henrik Sahlin Pettersen, Thevaasiinen Chandereng, Ioannis Koutroulis, Genevieve Stein-O’Brien, Dimitrios N Sidiropoulos, Vittorio Gallo, Panagiotis Kratimenos PMID: 40950223 bioRxiv [Preprint] 2025.09.01.673244. Sep 2, 2025
The shifting landscape of the preterm brain
Panagiotis Kratimenos, Georgios Sanidas, Gabriele Simonti, Chad Byrd, Vittorio Gallo PMID: 40239653 Neuron 113(13):2042-2064 Jul 9, 2025
Cerebellar Purkinje Cell Activity Regulates White Matter Response and Locomotor Function after Neonatal Hypoxia
Srikanya Kundu, Javid Ghaemmaghami, Georgios Sanidas, Nora Wolff, Abhya Vij, Chad Byrd, Gabriele Simonti, Maria Triantafyllou, Beata Jablonska, Terry Dean, Ioannis Koutroulis, Vittorio Gallo, Panagiotis Kratimenos PMID: 39472064 Journal of Neuroscience 45(1):e0899242024 Jan 1, 2025
Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia-ischemia
Frances J. Northington, Panagiotis Kratimenos, Victoria Turnbill, Debra L. Flock, Daniella Asafu-Adjaye, Raul Chavez-Valdez, Lee J. Martin PMID: 34687459 J Comp Neurol. 530(8):1148-1163. Oct 23 2021

SEE MORE PUBLICATIONS

Kratimenos Lab

About the Lab

Featured Publications

Prematurity reprograms cerebellar development and long-term behavior

Intrinsic gestational timing governs human cerebellar development after preterm birth

The shifting landscape of the preterm brain

Cerebellar Purkinje Cell Activity Regulates White Matter Response and Locomotor Function after Neonatal Hypoxia

Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia-ischemia

Related News

Understanding mechanisms of injury due to prematurity in human cerebellum

Neuroprotective effect of Src kinase in neonates affected by HIE

Neonatal hypoxia-ischemia causes damage to the cholinergic system